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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MRS-1706 ： ウィキペディア英語版 MRS-1706 |Section2= |Section3= }} MRS-1706 is a selective inverse agonist for the adenosine A2B receptor.〔Li Q, Ye K, Blad CC, den Dulk H, Brouwer J, Ijzerman AP, Beukers MW. ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor. ''Journal of Pharmacology and Experimental Therapeutics''. 2007 Feb;320(2):637-45. PMID 17077318〕 It inhibits release of interleukins and has an antiinflammatory effect.〔Vazquez JF, Clement HW, Sommer O, Schulz E, van Calker D. Local stimulation of the adenosine A2B receptors induces an increased release of IL-6 in mouse striatum: an in vivo microdialysis study. ''Journal of Neurochemistry''. 2008 May;105(3):904-9. PMID 18088370〕〔Ryzhov S, Zaynagetdinov R, Goldstein AE, Novitskiy SV, Dikov MM, Blackburn MR, Biaggioni I, Feoktistov I. Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells. ''Journal of Immunology''. 2008 Jun 1;180(11):7212-20. PMID 18490720〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MRS-1706」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.