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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MAPK8IP2 ： ウィキペディア英語版 MAPK8IP2 C-jun-amino-terminal kinase-interacting protein 2 is a protein or the name of the gene that encodes it.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23542 )〕 The gene is also known as Islet-Brain-2 (IB2). This protein is highly expressed in the brain and is almost always deleted in Phelan-McDermid syndrome (PMS). MAPK8IP2 appears to regulate the ratio of AMPA receptors to NMDA receptors at glutamate synapses, and thus may be an important contributor to the intellectual dysfunction and related neurological manifestations characteristic of PMS. ==Interactions== MAPK8IP2 has been shown to interact with MAP3K10,〔 Mitogen-activated protein kinase 9,〔 LRP2, LRP1,〔 MAPK8IP3, MAP3K12,〔 MAPK8IP1,〔 MAP2K7〔 and MAP3K11.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MAPK8IP2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.