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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lipo-oxytocin-1 ： ウィキペディア英語版 Lipo-oxytocin-1 Lipo-oxytocin-1 (LOT-1) is a synthetic peptide and analogue of oxytocin that acts as an agonist of the oxytocin receptor. The lipidation strategy was applied to oxytocin to create a new peptide with improved pharmacokinetics.〔 LOT-1 consists of oxytocin conjugated with two palmitoyl groups.〔 After adjusting for molecular weight (LOT-1 is ~1.5x the weight of oxytocin), oxytocin and LOT-1 are equipotent.〔 In addition, LOT-1 appears to have a significantly longer duration of effect relative to that of oxytocin.〔 It has yet to be determined whether LOT-1 possesses improved blood-brain-barrier permeability relative to oxytocin.〔 ==See also== * Carbetocin * Demoxytocin * Merotocin * Palmitoylation 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lipo-oxytocin-1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.