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・ Loxostege annaphilalis
・ Loxford
・ Loxford Park Speedway
・ Loxford School of Science and Technology
・ LOXHD1
・ Loxhore
・ Loxian
・ Loxicha Zapotec
・ Loxie & Zoot
・ Loxigilla
・ Loximuthal projection
・ Loxioda
・ Loxioda fasciosa
・ Loxioides
・ LOXL1
LOXL2
・ LOXL3
・ LOXL4
・ Loxley
・ Loxley Hall
・ Loxley House
・ Loxley House, Nottingham
・ Loxley, Alabama
・ Loxley, South Yorkshire
・ Loxley, Warwickshire
・ Loxmaionia
・ Loxo
・ Loxoblemmus
・ Loxocalyx
・ Loxocarpus


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LOXL2 : ウィキペディア英語版
LOXL2

Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the ''LOXL2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4017 )
== Function ==

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.〔
LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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