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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ISCOM ： ウィキペディア英語版 ISCOM Immune stimulating complexes (ISCOMs) are spherical open cage-like structures (typically 40 nm in diameter) that are spontaneously formed when mixing together cholesterol, phospholipids and Quillaia saponins under a specific stoichiometry. The complex displays immune stimulating properties and is thus mainly used as a vaccine adjuvant in order to induce a stronger immune response and longer protection. ==History== ISCOM technology was invented in 1982 by Professor Bror Morein at the Swedish University of Agricultural Sciences in Uppsala. The key components of ISCOMs are the Quillaja saponins, which are derived from the bark of the Chilean soap-bark tree Quillaja saponaria Molina. Quillaia saponins are well known for their ability to activate the immune system. It is also known that saponins in general can have toxic side-effects, including the induction of haemolysis. However, when Quillaia saponins, cholesterol and phospholipids are mixed under the specific stoichiometry that forms ISCOMs, this haemolytic activity is practically eliminated, while the adjuvant activity is retained. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ISCOM」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.