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Immunoglobulin kappa locus, also known as IGK@, is a region on human chromosome 2 that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins). In humans the κ chain is coded for by V (variable), J (joining) and C (constant) genes in this region.〔Male, D., Brostoff, J., Roth, D.B., & Roitt, I. 2006. Immunology. 7th ed., Canada: Elsevier Limited〕 These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins. == Genes == The immunoglobulin kappa locus contains the following genes: * IGKC: immunoglobulin kappa constant * IGKJ@: immunoglobulin kappa joining group * * IGKJ1, IGKJ2, IGKJ3, IGKJ4, IGKJ5 * IGKV@: immunoglobulin kappa variable group * * IGKV1-5, IGKV1-6, IGKV1-8, IGKV1-9, IGKV1-12, IGKV1-16, IGKV1-17, IGKV1-27, IGKV1-33 * * IGKV1D-8, IGKV1D-12, IGKV1D-13, IGKV1D-16, IGKV1D-17, IGKV1D-22, IGKV1D-27, IGKV1D-32, IGKV1D-33, IGKV1D-39, IGKV1D-43 * * IGKV2-24, IGKV2-28, IGKV2-30, IGKV2-40 * * IGKV2D-26, IGKV2D-28, IGKV2D-29, IGKV2D-30, IGKV2D-40 * * IGKV3-11, IGKV3-15, IGKV3-20 * * IGKV3D-7, IGKV3D-11, IGKV3D-20 * * IGKV4-1 * * IGKV5-2 * and a number of non-functional and pseudogenes 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「IGK@」の詳細全文を読む スポンサード リンク
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