翻訳と辞書
Words near each other
・ HNoMS Æger (1936)
・ HNoMS Ørnen
・ HNoMS Ørnen (1829)
・ HNoMY Norge
・ Hnonae
・ Hnoss
・ HNP
・ HNRNPA0
・ HNRNPC
・ HNRNPL
・ HNRNPLL
・ HNRNPR
・ HNRPA2B1
・ HNRPA3
・ HNRPAB
HNRPD
・ HNRPDL
・ HNRPF
・ HNRPH1
・ HNRPH2
・ HNRPH3
・ HNRPK
・ HNRPU
・ HNRPUL1
・ HNS
・ HnS
・ HNS Convention
・ HNSKY
・ HNT
・ HNTB


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HNRPD : ウィキペディア英語版
HNRPD

Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) also known as AU-rich element RNA-binding protein 1 (AUF1) is a protein that in humans is encoded by the ''HNRNPD'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3184 )〕 Alternative splicing of this gene results in four transcript variants.
== Function ==

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). The interaction sites on the RNA are frequently biased towards particular sequence motifs. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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