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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク HKDC1 ： ウィキペディア英語版 HKDC1 Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the ''HKDC1'' gene on chromosome 10.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/80201 )〕 It is a recently discovered hexokinase isoform that likely phosphorylates glucose in maternal metabolism during pregnancy. ==Structure== The ''HKDC1'' gene is oriented in a head-to-tail arrangement next to the ''HK1'' gene on chromosome 10.〔 This arrangement, along with its amino acid sequence similarity to HK1, suggests that ''HKDC1'' and ''HK1'' derived from the same precursor via a tandem gene duplication event.〔〔〔 The similarity between HKDC1 and HK1 may have obscured its discovery in earlier screens for vertebrate hexokinases.〔 Unlike the HK2 pseudogene, HKDC1 contains an intact open reading frame of 917 residues and is conserved across animal species, indicating that it encodes a functional protein. Moreover, the encoded protein contains conserved glucose-binding sites in its N- and C-terminal domains as well as an ATP-binding site in its C-terminal domain, indicating that its C-terminal is capable of hexokinase activity.〔〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「HKDC1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.