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HIRA
Protein HIRA is a protein that in humans is encoded by the ''HIRA'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7290 )〕 This gene is mapped to 22q11.21, centromeric to COMT.〔
== Function ==
The specific function of this protein has yet to be determined; however, it has been speculated to play a role in transcriptional regulation and/or chromatin and histone metabolism.〔
Research done by Salomé Adam, Sophie E. Polo, and Geneviève Almouzni indicate that HIRA proteins are involved in restarting transcription after UVC damage〔Adam, S., Polo, S. E., & Almouzni, G. (2013). Transcription Recovery after DNA Damage Requires Chromatin Priming by the H3.3 Histone Chaperone HIRA. Cell, 155(1), 94-106. Retrieved from http://www.cell.com/abstract/S0092-8674(13)01023-4〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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