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Genotype to Phenotype Databases: a Holistic Approach (GEN2PHEN) is a European project aiming to develop a knowledge web portal integrating information from the genotype to the phenotype in a unifying (portal: The Knowledge Centre ).〔http://precedings.nature.com/documents/1784/version/1/files/npre20081784-1.pdf〕〔http://nar.oxfordjournals.org/cgi/content/abstract/gkn748〕〔http://www.gen2phen.org/system/files/private/poster%20ESHG%20Vienna%202009%20ResID.pdf〕〔http://open-bio.org/w/images/6/6e/17_BOSC2010.pdf〕〔http://www.iscb.org/uploaded/css/58/17288.pdf〕 ==Summary and Objectives== The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seamless G2P biomedical knowledge environment, by the projects end. This will consist of a European-centred but globally networked hierarchy of bioinformatics GRID-linked databases, tools and standards, all tied into the Ensembl genome browser. The project has the following specific objectives: * To analyse the G2P field and thus determine emerging needs and practices * To develop key standards for the G2P database field * To create generic database components, services and integration infrastructures for the G2P database domain * To create search modalities and data presentation solutions for G2P knowledge * To facilitate the process of populating G2P databases * To build a major G2P internet portal * To deploy GEN2PHEN solutions to the community * To address system durability and long-term financing * To undertake a whole-system utility and validation pilot study The GEN2PHEN Consortium members have been selected from a talented pool of European research groups and companies that are interested in the G2P database challenge. Additionally, a few non-EU participants have been included to bring extra capabilities to the initiative. The final constellation is characterised by broad and proven competence, a network of established working relationships, and high-level roles/connections within other significant projects in this domain... 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「GEN2PHEN」の詳細全文を読む スポンサード リンク
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