翻訳と辞書
Words near each other
・ FC Augsburg–TSV 1860 München rivalry
・ FC Avangard
・ FC Avangard Kamyshin
・ FC Avangard Kursk
・ FC Avangard Podolsk
・ FC Avangard-Kortek
・ FC Avanhard Kramatorsk
・ FC Avanhard Rovenky
・ FC Avanhard Ternopil
・ FC Avanhard Zhydachiv
・ FC Avenir Beggen
・ FC Avers Bakhmach
・ FC Avirons
・ FBXO28
・ FBXO31
FBXO32
・ FBXO4
・ FBXO5
・ FBXO6
・ FBXO7
・ FBXO9
・ FBXW10
・ FBXW11
・ FBXW2
・ FBXW4
・ FBXW5
・ FBXW7
・ FBXW8
・ FC
・ FC (band)


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

FBXO32 : ウィキペディア英語版
FBXO32

F-box only protein 32 is a protein that in humans is encoded by the ''FBXO32'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114907 )
== Function ==

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「FBXO32」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.