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Ehrlichiosis is a tickborne〔(【引用サイトリンク】date=15 November 2013 )〕 bacterial infection, caused by bacteria of the family Anaplasmataceae, genera ''Ehrlichia'' and ''Anaplasma''. These obligate intracellular bacteria infect and kill white blood cells. The average reported annual incidence is 0.7 cases per million people. ==Species== Five (see note below) species have been shown to cause human infection: * ''Anaplasma phagocytophilum'' (which causes human granulocytic anaplasmosis, formerly known as human granulocytic ehrlichiosis). ''A. phagocytophilum'' is endemic to New England and the north central and Pacific regions of the United States. * ''Ehrlichia ewingii'' (which causes human ewingii ehrlichiosis). ''E. ewingii'' primarily infects deer and dogs (see Ehrlichiosis (canine)).〔 ''E. ewingii'' is most common in the south central and southeastern states. * ''Ehrlichia chaffeensis'' (which causes human monocytic ehrlichiosis). ''E. chaffeensis'' is most common in the south central and southeastern states. * ''Ehrlichia canis'' * ''Neorickettsia sennetsu'' The latter two infections are not well studied. In 2006, human infection by Boone County, Missouri. Symptoms: high fever,severe joint and muscle aches, vomiting. Onset of symptoms began exactly 14 days after bite occurred. Symptoms affected patient on a 12-hour cycle; beginning early evening, ending early morning. No symptoms occurred for next 12 hours. CBC presented low WBC. Note: In 2008, human infection by Panola Mountain (Georgia, USA) ''Ehrlichia'' species was reported. On August 3, 2011, infection by a yet-unnamed bacterium in the genus ''Ehrlichia'' carried by deer ticks that has caused flu-like symptoms in at least 25 people in Minnesota and Wisconsin was reported; human ehrlichiosis was thought to be very rare or absent in Minnesota and Wisconsin. The new species, which is very similar genetically to an ''Ehrlichia'' species found in Eastern Europe and Japan called ''E. muris'', was identified at Mayo Clinic Health System's Eau Claire hospital.〔 ''Ehrlichia'' are transported between cells through the host cell filopodia during initial stages of infection, whereas, in the final stages of infection the pathogen ruptures the host cell membrane. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ehrlichiosis」の詳細全文を読む スポンサード リンク
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