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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Dopexamine ： ウィキペディア英語版 Dopexamine Dopexamine is a synthetic analogue of dopamine. Despite this, it is a β1 and β2-adrenergic receptor agonist. Its action at dopamine receptor D1 mediates relaxation of vascular smooth muscle in renal, mesenteric, cerebral and coronary arteries. Mild action at D2 receptors decreases noradrenaline release. Use in sepsis has been proposed. It is used as an inotropic agent in cardiac failure. Side effects include arrhythmia, tremor, angina and flushing. ==Synthesis== Condensation of the adipic acid derivative 1 with phenethylamine in the presence of Carbonyldiimidazole affords bis-adipic acid amide 2. The synthesis is completed by reduction of the carbonyl groups with diborane followed by demethylation of the aromatic methoxy groups with hydrogen bromide to afford dopexamine. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dopexamine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.