翻訳と辞書 Words near each other ・ DGA Essais de missiles ・ DGa'-ldan ・ DGAC ・ DGamer ・ DGB Financial Group ・ DGBX ・ DGC ・ DGC Rarities Vol. 1 ・ DGC Records ・ DGCA ・ DGCA (computing) ・ DGCR14 ・ DGCR2 ・ DGCR5 ・ DGCR6 ・ DGCR8 ・ DGCX ・ DGD ・ DGDG synthase ・ DGE ・ Dgebuadze ・ Dgebuadze (noble family) ・ DGEG ・ DGenerate Films ・ DGF ・ DGF Flensborg ・ DGFM flamethrower ・ DGG ・ DGH ・ DGH (disambiguation) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク DGCR8 ： ウィキペディア英語版 DGCR8 The DGCR8 microprocessor complex subunit ''(DiGeorge syndrome chromosomal'' (''critical'' ) ''region 8)'' is a protein that in humans is encoded by the ''DGCR8'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54487 )〕 In other animals, particularly the common model organisms ''Drosophila melanogaster'' and ''Caenorhabditis elegans'', the protein is known as ''Pasha'' (partner of Drosha). It is a required component of the RNA interference pathway. == Function == DGCR8 is localized to the cell nucleus and is required for microRNA (miRNA) processing. It binds to Drosha, an RNase III enzyme, to form the ''Microprocessor complex'' that cleaves a primary transcript known as pri-miRNA to a characteristic stem-loop structure known as a pre-miRNA, which is then further processed to miRNA fragments by the enzyme Dicer. DGCR8 contains an RNA-binding domain and is thought to bind pri-miRNA to stabilize it for processing by Drosha. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「DGCR8」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.