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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク DAP3 ： ウィキペディア英語版 DAP3 28S ribosomal protein S29, mitochondrial, also known as death-associated protein 3 (DAP3), is a protein that in humans is encoded by the ''DAP3'' gene on chromosome 1.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7818 )〕 This gene encodes a 28S subunit protein of the mitochondrial ribosome (mitoribosome) and plays key roles in translation, cellular respiration, and apoptosis.〔〔 Moreover, DAP3 is associated with cancer development, but has been observed to aid some cancers while suppressing others.〔 ==Structure== The ''DAP3'' gene encodes a 46 kDa protein located in the lower area of the small mitoribosomal subunit.〔〔 This protein contains a P-loop motif that binds GTP and a highly conserved 17-residue targeting sequence responsible for its localization to the mitochondria.〔〔〔〔 Of interest, many of the phosphorylation sites on this protein are highly conserved and clustered around GTP-binding motifs.〔 Several splice variants were observed in human ESTs that differ largely in the 5’ UTR region.〔〔 Pseudogenes for this gene are also found in chromosomes 1 and 2.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「DAP3」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.