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Colestipol (trade names Colestid, Cholestabyl) is a bile acid sequestrant used to lower blood cholesterol, specifically low-density lipoprotein (LDL).〔Drugs.com: (Colestipol Hydrochloride )〕 It is also used to reduce stool volume and frequency, and in the treatment of chronic diarrhea.〔http://www.medicinenet.com/colestipol/article.htm〕 Like cholestyramine, colestipol works in the gut by trapping bile acids and preventing them from being reabsorbed. This leads to decreased enterohepatic recirculation of bile acids, increased synthesis of new bile acids by the liver from cholesterol, decreased liver cholesterol, increased LDL receptor expression, and decreasing LDL in blood. ==Side effects== The following notable side effects may occur:〔 * gastrointestinal tract disturbances, especially (mild, occasionally severe) constipation * sometimes increase in VLDL and triglyceride synthesis 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Colestipol」の詳細全文を読む スポンサード リンク
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