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Codexis
Codexis, Inc. engineers enzymes for pharmaceutical and chemical production. Codexis’ technologies enable scale-up and implementation of biocatalytic solutions to optimize process development, from research to manufacturing. There are currently over 50 pharmaceutical firms using Codexis’ technology, products and services in their manufacturing process development.
Codexis creates its products by applying its CodeEvolver® directed evolution technology platform, which introduces genetic mutations into microorganisms.
== Pharmaceutical Enzymes, Intermediates and Services ==
Codexis markets and sells enzymes, development services and screening tools, providing manufacturing processes for active pharmaceutical ingredients (APIs), and their precursor pharmaceutical intermediates.
Codexis customers include major companies such as Merck, Pfizer, and Teva that use Codexis' custom biocatalysts to create more sustainable, less costly manufacturing processes for new and existing drugs. Codexis' biocatalysts are being used in the manufacturing process for the cholesterol-fighting drug Lipitor and are in development for the manufacturing of the diabetes drug Januvia. Codexis won the Presidential Green Chemistry Challenge Award from the U.S. Environmental Protection Agency (EPA) in 2006 for its work on a building block of Lipitor 〔http://ir.codexis.com/phoenix.zhtml?c=208899&p=irol-newsArticle&ID=1181061〕 and a second time with Merck in 2010 for its work on the active ingredient in Januvia.〔http://www.reuters.com/article/2010/06/17/merck-green-idUSN1727061820100617〕
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