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Catalpol : ウィキペディア英語版
Catalpol

Catalpol is an iridoid glucoside . This natural product falls in the class of iridoid glycosides, which are simply monoterpenes with a glucose molecule attached. Although the pharmacological action of catalpol as well as many other iridoids has not been fully established, there is evidence that their primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.
== Natural occurrences ==
First isolated in 1962, catalpol was named for plants in the genus ''Catalpa'' in which it was discovered. Later in 1969, catalpol was found to be present in larger quantities in several plants in genus ''Rehmannia'' (Orobanchaceae).
It is found in plants belonging to several families, including, but not limited to, Scrophulariaceae, Lamiaceae (including scullcap〔Yaghmai and Benson, 1979
M.S. Yaghmai, G.G. Benson The wax hydrocarbons of Scutellaria lateriflora L Manchester, England (1979) 228–229 p〕), Plantaginaceae (''Plantago sp'') and Bignoniaceae, all of which being in the order Lamiales.
Because they feed on these plants, Variable Checkerspot butterflies contain high amounts of catalpol,〔Stermitz, Frank R., Maged S. Abdel-Kader, Tommaso A. Foderaro, and Marc Pomeroy. "Iridoid Glycosides from Some Butterflies and Their Larval Food Plants." Phytochemistry 37.4 (1994): 997-99.〕 which makes them unpalatable to predators and thus serves as a defense mechanism.〔Bowers, M. D. "Unpalatability as a Defense Strategy of Western Checkerspot Butterflies (Euphydryas Scudder, Nymphalidae)." Evolution 35.2 (1981): 367-75.〕

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