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・ CX 38 SODRE
・ CX 4 Radio Rural
・ CX 40 Radio Fénix
・ CX 42 Emisora Ciudad de Montevideo
・ CX 44
・ CX 46 Radio América
・ CX 58 Radio Clarín
・ CX 6 SODRE
・ CX 8 Radio Sarandí
・ CX Navarro
・ CX-5
・ CX-516
・ CX-546
・ CX157
・ CX3CL1
CX3CR1
・ Cx4
・ CX614
・ CX717
・ CXAM radar
・ CXC chemokine receptors
・ CXCL1
・ CXCL10
・ CXCL11
・ CXCL13
・ CXCL14
・ CXCL15
・ CXCL16
・ CXCL17
・ CXCL2


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CX3CR1 : ウィキペディア英語版
CX3CR1

CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) is a protein that in humans is encoded by the ''CX3CR1'' gene. As the name suggests, this receptor binds the chemokine CX3CL1 (also called neurotactin or fractalkine).
== Function ==

The fractalkine ligand CX3CL1 is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by the CX3R1 gene is a receptor for the fractalkine ligand.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1524 )
Expression of this receptor appears to be associated with lymphocytes. CX3CR1 is also expressed by monocytes and plays a major role in the survival of monocytes.
Fractalkine signalling has also recently been discovered to play a developmental role in the migration of microglia in the central nervous system to their synaptic targets, where phagocytosis and synaptic refinement occur. CX3CR1 knockout mice had more synapses on cortical neurons than wild-type mice.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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