翻訳と辞書
Words near each other
・ CCL13
・ CCL14
・ CCL15
・ CCL16
・ CCL17
・ CCL18
・ CCL19
・ CCL2
・ CCL20
・ CCL21
・ CCL22
・ CCL23
・ CCL24
・ CCL25
・ CCL26
CCL27
・ CCL28
・ CCL3
・ CCL3L1
・ CCL4
・ CCL4L1
・ CCL5
・ CCL6
・ CCL7
・ CCL8
・ CCL9
・ CCLA
・ CCLC
・ CCleaner
・ CCLM


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

CCL27 : ウィキペディア英語版
CCL27

Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). It is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin.〔Morales et al. CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc. Natl. Acad. Sci. U.S.A. 96:14470-14475, 1999.〕〔Homey et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nature Med. 8: 157-165, 2002.〕 CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotactic effects by binding to the chemokine receptor CCR10.〔Homey et al. The orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J. Immunol. 164:3465-3470, 2000.〕 The gene for CCL27 is located on human chromosome 9.〔Ishikawa-Mochizuki et al. Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of a CC chemokine encoded by molluscum contagiosum virus. FEBS Lett. 460:544-548, 1999.〕
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「CCL27」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.