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・ CCIR System M
・ CCIS
・ Ccis
・ CCISD
・ CCIVS
・ CCJ
・ CCJO René Cassin
・ CCK
・ CCK-4
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・ CCKM
・ CCL
・ CCL Industries
・ CCL Label Decorative Sleeves
・ CCL1
CCL11
・ CCL12
・ CCL13
・ CCL14
・ CCL15
・ CCL16
・ CCL17
・ CCL18
・ CCL19
・ CCL2
・ CCL20
・ CCL21
・ CCL22
・ CCL23
・ CCL24


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CCL11 : ウィキペディア英語版
CCL11

C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.〔
== Function ==

CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5.〔 However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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