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CACNA2D4 : ウィキペディア英語版
CACNA2D4

Calcium channel, voltage-dependent, alpha 2/delta subunit 4 is a protein that in humans is encoded by the CACNA2D4 gene.

(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/93589 )
==Function==

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. (by RefSeq, Jul 2008 ). ##Evidence-Data-START## Transcript exon combination :: BX537437.1, AF516695.1 () RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 () ##Evidence-Data-END##

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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