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Biomonitoring : ウィキペディア英語版
Biomonitoring


In analytical chemistry, biomonitoring is the measurement of the body burden〔(What is body burden? )〕 of toxic chemical compounds, elements, or their metabolites, in biological substances. Often, these measurements are done in blood and urine.〔
The two best established biomonitoring programs in representative samples of the general population are those of the United States and Germany, although population-based programs exist in a few other countries.〔Porta M, et al. Monitoring concentrations of persistent organic pollutants in the general population: the international experience. Environment International 2008; 34: 546–561.〕 In 2001, the U.S. Centers for Disease Control and Prevention (CDC) began to publish its biennial ''National Report on Human Exposure to Environmental Chemicals'', which reports a statistically representative sample of the U.S. population. The Environmental Working Group has also conducted biomonitoring studies.〔
==Overview==

Historically, public health regulations have been based on theoretical risk calculations according to known levels of chemical substances in air, water, soil, food, other consumer products and other sources of potential exposure. Human biomonitoring offers the opportunity to analyze the actual internal levels of bodily substances from all potential routes of exposure at one time, which may contribute to improving risk assessments. Scientific advancements have made it possible to detect a greater number of chemical substances in smaller concentrations in the body, with some chemicals detectable at levels as low as parts per trillion. A single biomonitoring measurement is only one snapshot in time and may not accurately reflect the level of exposure over longer periods.
In 2006 the U.S. National Research Council published a report, ''Human Biomonitoring for Environmental Chemicals''. The report recognized the value of biomonitoring for better understanding exposure to environmental chemicals, and included several findings and recommendations to improve the utility of biomonitoring data for health risk assessment. In summary, the report called for more rigorous health-based criteria for selecting chemicals to include in biomonitoring studies; the development of tools and techniques to improve risk-based interpretation and communication of biomonitoring data; integration of biomonitoring into exposure assessment and epidemiological research; and exploration of bioethical issues around biomonitoring, including informed consent, confidentiality of results, and others.〔(【引用サイトリンク】 work = acs.org )
The issue of exposure to environmental chemicals has received attention as a result of televised reports by Bill Moyers for PBS and Anderson Cooper for CNN's "Planet in Peril" series. The book ''Our Stolen Future'', with a foreword by former Vice President Al Gore, also raised awareness by focusing on endocrine disruption.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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