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Belinostat : ウィキペディア英語版
Belinostat

Belinostat (trade name Beleodaq, previously known as PXD101) is a drug developed by TopoTarget for the treatment of hematological malignancies and solid tumors. It is a histone deacetylase inhibitor.
In 2007 preliminary results were released from the Phase II clinical trial of intravenous belinostat in combination with carboplatin and paclitaxel for relapsed ovarian cancer. Final results in late 2009 of a phase II trial for T-cell lymphoma were encouraging.
Belinostat has been granted orphan drug and fast track designation by the FDA, and was approved in the US for the use against peripheral T-cell lymphoma. It is not approved in Europe .
==References==



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