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BAALC
BAALC (''Brain and Acute Leukemia, Cytoplasmic'')is a gene that has been associated with acute myeloid leukemia. The gene is conserved among mammals and is not found in lower organisms.〔http://www.genecards.org/cgi-bin/carddisp.pl?gene=BAALC〕〔http://www.pnas.org/content/98/24/13901.abstract〕 Tissues that express this gene develop from the neuroectoderm.〔 Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines.〔 Among patients with acute myeloid leukemia, those overexpressing BAALC show distinctly poor prognosis, pointing to a key role of the BAALC products in leukemia.〔 Some sources suggest that BAALC is a gene implicated in both neuroectodermal and hematopoietic cell functions.〔 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「BAALC」の詳細全文を読む
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