翻訳と辞書 Words near each other ・ Anmar ・ Ankola (skipper) ・ Ankole ・ Ankole mole-rat ・ Ankole sub-region ・ Ankole Western University ・ Ankole-Watusi ・ Ankondromena ・ Ankoro ・ Ankotarinja ・ Ankotrofotsy ・ Ankou ・ Ankova ・ Ankpa ・ Ankrah (surname) ・ ANKRD1 ・ ANKRD13C ・ ANKRD15 ・ ANKRD17 ・ ANKRD2 ・ ANKRD23 ・ ANKRD25 ・ ANKRD26 ・ ANKRD27 ・ ANKRD35 ・ Ankrum ・ Ankrurahu ・ ANKS1A ・ ANKS1B ・ ANKS4B Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ANKRD1 ： ウィキペディア英語版 ANKRD1 CARP, also known as Cardiac adriamycin-responsive protein or Cardiac ankyrin repeat protein is a protein that in humans is encoded by the ''ANKRD1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27063 )〕 CARP is highly expressed in cardiac and skeletal muscle, and is a transcription factor involved in development and under conditions of stress. CARP has been implicated in several diseases, including dilated cardiomyopathy, hypertrophic cardiomyopathy, and several skeletal muscle myopathies. ==Structure== Human CARP is a 36.2kDa protein composed of 319 amino acids.,〔(【引用サイトリンク】url=http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=Q15327 )〕 though in cardiomyocytes, CARP can exist as multiple alternatively spliced forms. CARP contains five tandem ankyrin repeats. Studies have shown that CARP can homodimerize. Studies have also shown that CARP is N-terminally, post-translationally cleaved by calpain-3 in skeletal muscle, suggesting alternate bioactive forms of CARP exist. CARP has been localized to nuclei and Z-discs in animal and human myocytes, and at intercalated discs in human cells. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ANKRD1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.