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NNE1 : ウィキペディア英語版
NNE1

NNE1 (also known as NNEI, MN-24 and AM-6527) is an indole-based synthetic cannabinoid, representing a molecular hybrid of APICA and JWH-018. It was invented by Abbott and has a CB1 receptor pEC50 of 8.9 (i.e. EC50 of approximately 1nM) with around 80x selectivity over the related CB2 receptor. It is suspected that metabolic hydrolysis of the amide group of NNE1 may release 1-naphthylamine, a known carcinogen, given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, and NNE1 was banned in New Zealand in 2012 as a temporary class drug to stop it being used as an ingredient in then-legal synthetic cannabis products.〔(New Zealand Government Gazette, Notice Number 7051, 1 November 2012 )〕 NNE1 was subsequently found to be responsible for the death of a man in Japan in 2014.
==See also==

* 5F-NNE1
* 5F-PCN
* AM-2201
* APICA
* CUMYL-PICA
* FDU-NNE1
* JWH-018
* NM-2201
* SDB-005

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「NNE1」の詳細全文を読む



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