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Ladeana Hillier
Ladeana Hillier is a biomedical engineer and computational biologist.〔Wenz, C (2005) ''Author Profile: Ladeana Hillier.'' Nurture 1, pp. 2.〕 She was one of the earliest scientists involved in the Human Genome Project〔Sulston, J and Ferry, G (2002) ''The Common Thread: A Story of Science, Politics, Ethics, and the Human Genome'', Joseph Henry Press.〕 and is noted for her work in various branches of DNA sequencing,〔Hillier, LW ''et al.'' (2003) ''The DNA sequence of human chromosome 7.'' Nature 424(6945), 157–164.〕〔Hillier, LW ''et al.'' (2005) ''Generation and annotation of the DNA sequences of human chromosomes 2 and 4.'' Nature 434(7034), 724–731.〕〔Hillier, LW ''et al.'' (2004) ''Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.'' Nature 432(7018), 695–716.〕〔Hillier, LW ''et al.'' (2008) ''Whole-genome sequencing and variant discovery in C-elegans.'' Nature Methods 5(2), 183–188.〕〔Hillier, LW ''et al.'' (1996) ''Generation and analysis of 280,000 human expressed sequence tags.'' Genome Research 6(9), 807–828.〕 as well as for having co-developed Phred,〔Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Research 8(3), 175–185. PMID 9521921 (full article )〕 a widely used DNA trace analyzer.〔Koboldt, D. C. and Miller, R. D. (2011) ''Identification of Polymorphic Markers for Genetic Mapping'', chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.〕〔Highsmith, W. E. (2006) ''Electrophoretic Methods for Mutation Detection and DNA Sequencing'', chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press〕
==See also==
*Phred base calling
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